SPECIFIC OBJECTIVE4

ACTIVITY 4.1: Development of air pollutants concentration maps with very high spatial resolution (1-5m2) accounting for the complexity of the topographic configuration of urban environment. This methodwill be applied to a large portion of the metropolitan area ofRomefor the year 2015. Micro-scale Lagrangian particle models will be used, with estimation of fluid dynamics effects due to urban  factories.

ACTIVITY 4.2: Estimate of noise levels at individual building level within the areas of Rome and Pisa, based on available or prototype traffic flows, deduced from population data derived from mobile phone use for the year 2015.

ACTIVITY 4.3: Determination of air pollutants concentration maps within the area of Pisa, at a spatial resolution of a few hundred meters, using data fusion techniques, based on the results of Activity 1.1, of observed data of pollutants concentration provided by monitoring stations and of territorial data.

ACTIVITY 4.4: Retrieval of data of Rome Longitudinal Study, a closed administrative cohort of 1.2 million subjects, enrolled in October 2001 and followed until 2013.

ACTIVITY 4.5: Retrieval of data of Pisa/Cascina Longitudinal Study, a general population cohort of 4000 subjects enrolled in the 80s and followed until 2011 by the Pulmonary Environmental Epidemiology Unit of the CNR Institute of Clinical Physiology (CNR- IFC) of Pisa (with which CNR-IBIM has close working relationships).

ACTIVITY 4.6: Joint assessment of the health effects of air pollutants, temperature and urban noise on mortality and incidence of different diseases (cardiovascular, respiratory, diabetes, anxiety and depression) in the Rome Longitudinal Study mentioned in Activity 4.4.

ACTIVITY 4.7: Joint evaluation of the health effects of air pollutants, temperature and urban noise on mortality and incidence of different diseases (cardiovascular, respiratory) in the Pisa/Cascina Longitudinal Study mentioned in Activity 4.5.

ACTIVITY 4.8: Assessment of the effects of heavy rain and extreme temperatures on road accidents and injuries in Rome. For the environmental exposure, rainfall data of the pluviometric monitoring network of the Lazio Region and temperature data described in Activity 1.2 will be considered, while for the effects (road accidents / injuries), data coming from different sources of information (SIES, ARES, Local Police Rome capital) will be considered. Mobile phone data will be used to take into account traffic flows, in particular, of the main commuting trajectories for work reasons, in relation to road accidents.